Isitoreji Sokugomela i-Covid-19

Uyini Umgomo we-Covid-19?
Umuthi wokugomela i-Covid - 19, othengiswa ngaphansi kwegama lomkhiqizo i-Comirnaty, umuthi wokugomela osuselwa ku-mRNA we-Covid - 19.Yenzelwe izivivinyo zemitholampilo kanye nokukhiqiza.Umuthi wokugoma unikezwa ngomjovo we-intramuscular, odinga imithamo emibili inikezwe amasonto amathathu ngokuhlukana.Ungomunye wemithi emibili ye-RNA eyasetshenziswa ngokumelene ne-Covid-19 ngo-2020, kanti omunye umgomo weModerna.

Umuthi wokugoma bekuwumgomo wokuqala we-COVID - 19 ukugunyazwa isiphathimandla esilawulayo ukuze usetshenziswe izimo eziphuthumayo futhi owokuqala wasulelwa ukusetshenziswa njalo.NgoZibandlela wezi-2020, i-United Kingdom yaba yizwe lokuqala ukugunyaza umgomo esimweni esiphuthumayo, ngokushesha yalandelwa yi-United States, i-European Union namanye amazwe amaningana emhlabeni jikelele.Emhlabeni jikelele, izinkampani zihlose ukukhiqiza imithamo engaba yizigidi eziyizinkulungwane ezingu-2.5 ngo-2021. Kodwa-ke, ukusatshalaliswa nokugcinwa komgomo kuyinselele yokusingatha izinto ngoba udinga ukugcinwa emazingeni okushisa aphansi kakhulu.

Yiziphi izithako ekugomeni i-Covid-19?
Umuthi wokugoma i-Pfizer BioNTech Covid-19 uwumgomo we-RNA (mRNA) oyisithunywa onazo zombili izingxenye zokwenziwa, noma ezikhiqizwe ngamakhemikhali, kanye nezakhi ezikhiqizwe nge-enzyme ezivela ezintweni ezivele ngokwemvelo njengamaphrotheni.Umuthi wokugoma awunalo igciwane eliphilayo.Izithako zayo ezingasebenzi zihlanganisa i-potassium chloride, i-potassium monobasic, i-phosphate, i-sodium chloride, i-dibasic sodium phosphate dihydrate, ne-sucrose, kanye nenani elincane lezinye izithako.

Ukugcinwa Komgomo we-Covid-19
Njengamanje, umgomo kufanele ugcinwe efrijini eliphansi kakhulu emazingeni okushisa aphakathi kuka -80ºC kanye -60ºC, lapho ungagcinwa khona izinyanga eziyisithupha.Ingase futhi ifakwe esiqandisini izinsuku ezingafika kweziyisihlanu ezingeni lokushisa elivamile lesiqandisi (phakathi kuka + 2⁰C no + 8⁰C) ngaphambi kokuxuba ne-saline diluent.

Ithunyelwa ngesitsha esiklanywe ngokukhethekile esingasetshenziswa njengesitoreji sesikhashana kufika ezinsukwini ezingu-30.

Kodwa-ke, i-Pfizer ne-BioNTech basanda kuhambisa idatha entsha kwa-US Food and Drug Administration (FDA) ekhombisa ukuzinza komgomo wabo we-Covid-19 emazingeni okushisa afudumele.Idatha entsha ibonisa ukuthi ingagcinwa phakathi kuka -25 ° C kuya -15 ° C, amazinga okushisa avame ukutholakala kumafriji emithi naseziqandisini.

Ukulandela le datha, i-EU kanye ne-FDA e-USA zigunyaze lezi zimo ezintsha zokugcina ezivumela umgomo ukuthi manje ugcinwe emazingeni okushisa ajwayelekile efriji yezemithi ingqikithi yamasonto amabili.

Lesi sibuyekezo sezidingo zamanje zesitoreji somuthi wokugomela i-Pfizer sizobhekana nemikhawulo ethile mayelana nokuthunyelwa kwe-jab futhi singavumela ukukhishwa kalula komgomo emazweni antula ingqalasizinda yokweseka amazinga okushisa aphansi kakhulu esitoreji, okwenza ukusatshalaliswa kube kuncane. ukukhathazeka.

Kungani izinga lokushisa lokugcina Lomgomo we-Covid-19 libanda kangaka?
Isizathu sokuthi umuthi wokugomela i-Covid-19 udinga ukugcinwa ubanda kangaka kungenxa ye-mRNA ngaphakathi.Ubuchwepheshe bokusebenzisa i-mRNA buye baba semqoka ekwakheni umuthi wokugoma ophephile, osebenza ngokushesha, kodwa i-mRNA ngokwayo intekenteke ngendlela emangalisayo njengoba iphuka ngokushesha futhi kalula.Lokhu kungazinzi yikhona okwenze ukwakha umgomo osuselwa ku-mRNA kwaba inselele esikhathini esedlule.

Ngenhlanhla, umsebenzi omningi manje usungenile ekuthuthukiseni izindlela nobuchwepheshe okwenza i-mRNA izinze, ngakho ingafakwa ngempumelelo emuthini wokugoma.Kodwa-ke, imigomo yokuqala ye-Covid-19 mRNA isazodinga ukugcinwa okubandayo cishe ku-80ºC ukuze kuqinisekiswe ukuthi i-mRNA engaphakathi komgomo ihlala izinzile, okubanda kakhulu kunalokho okungafinyelelwa yifriji evamile.Lawa mazinga okushisa abandayo adingeka kuphela ukuze ugcinwe njengoba umgomo uncibilika ngaphambi komjovo.

Imikhiqizo ye-Carebios Yokugcina Umgomo
Iziqandisi zokushisa eziphansi kakhulu zikaCarebios zinikeza isisombululo sokugcina izinga lokushisa eliphansi kakhulu, elilungele umgomo we-Covid-19.Iziqandisi zethu zokushisa eziphansi kakhulu, ezaziwa nangokuthi iziqandisi ze-ULT, ngokuvamile zinebanga lokushisa elisukela -45 ° C kuya -86 ° C futhi zisetshenziselwa ukugcinwa kwezidakamizwa, ama-enzyme, amakhemikhali, amagciwane namanye amasampula.

Iziqandisi zethu zokushisa okuphansi ziyatholakala ngemiklamo nosayizi abahlukahlukene kuye ngokuthi singakanani isitoreji esidingekayo.Ngokuvamile kunezinguqulo ezimbili, ifriji eqondile noma ifriji yesifuba enokufinyelela engxenyeni engenhla.Ivolumu yesitoreji sangaphakathi ngokuvamile ingaqala ukusuka kumthamo wangaphakathi ongu-128 litres ifike kumthamo omkhulu ongu-730 wamalitha.Ivamise ukuba namashalofu ngaphakathi lapho amasampuli ocwaningo abekwa khona futhi ishalofu ngalinye livalwa ngomnyango wangaphakathi ukuze kugcinwe izinga lokushisa lifane ngendlela okungakhonakala ngayo.

-86 ° C uhla lwethu lwamafriji okushisa aphansi kakhulu luqinisekisa ukuvikelwa okuphezulu kwamasampuli ngaso sonke isikhathi.Ukuvikela isampula, umsebenzisi kanye nendawo ezungezile, iziqandisi zethu zokushisa eziphansi zenziwa ngokwezindinganiso zamazwe ngamazwe okusho ukusebenza okuwonga kwamandla okukongela imali nokusiza ukugcina ukukhishwa kwemvelo kuphansi.

Ngenani elingenakuhlulwa lemali, izinga lokushisa eliphansi lethu leziqandisi lilungele ukugcinwa kwesampula yesikhathi eside.Amavolumu ahlongozwayo asukela ku-128 kuya ku-730L.

Amafriji aphansi kakhulu aklanyelwe ukuphepha okuphezulu ngenxa yedizayini eqinile, ehlinzeka ngokulungiswa kalula futhi ethobela imithetho emisha yemvelo ye-F-Gas.

Thinta Ukuze uthole Ulwazi Olwengeziwe
Ukuze uthole okwengeziwe mayelana neziqandisi eziphansi zokushisa esizinikezayo kwa-Carebios noma ukubuza ngesiqandisi sezinga lokushisa eliphansi kakhulu ukuze ugcine umgomo we-Covid-19, sicela ungangabazi ukuthintana nelungu lethimba lethu namuhla.